The U.S. EPA’s Other Test Method (OTM)-50 establishes a consistent approach for measuring 30 volatile PFAS and other fluorinated compounds from stationary sources. These include breakdown products that can form during incomplete destruction or combustion, important indicators of how effectively PFAS treatment and destruction technologies perform.
As the industry moves toward more rigorous evaluation of PFAS destruction technologies and their ability to mineralize PFAS, not just degrade to other potentially harmful compounds, the need for reliable air measurements is essential. OTM-50 provides a technical framework for generating actionable data, and SGS is equipped to support its full implementation.
Until now, the industry has focused primarily on separating or sequestering PFAS on adsorptive media, but with recent advances in destructive techniques and additional research on combustion, the concern over unintended harmful by-products have also increased. That’s why OTM-50 matters: it provides an analytical framework needed to verify that destruction is complete, and to understand what’s being emitted.
Why SGS
As the global leader in PFAS analysis, SGS offers unmatched technical depth and analytical infrastructure to support OTM-50 projects.
Our network provides:
- Certified clean canisters for accurate sampling
- Comprehensive logistical support for complex field deployments
- Validated GC-MS/MS analysis for the full OTM-50 compound list
- Expert interpretation and regulatory insight from our PFAS specialists
From remediation system testing to emissions verification, SGS ensures the reliability and defensibility of your OTM-50 data.
Find the full OTM-50 Analyte List below.
Compound Name |
CAS # |
Chemical Formula |
| Carbon tetrafluoride | 75-73-0 | CF4 |
| Hexafluoroethane (FC-116) | 76-16-4 | C2F6 |
| Tetrafluoroethene | 116-14-3 | C2F4 |
| Trifluoromethane (HFC-23) | 75-46-7 | CHF3 |
| Octafluoropropane | 76-19-7 | C3F8 |
| Difluoromethane (HFC-32) | 75-10-5 | CH2F2 |
| Fluoromethane (HFC-41) | 593-53-3 | CH3F |
| Pentafluoroethane (HFC-125) | 354-33-6 | C2HF5 |
| Hexafluoropropene | 116-15-4 | C3F6 |
| Hexafluoropropene oxide (HFPO) | 428-59-1 | C3F6O |
| Decafluorobutane | 355-25-9 | C4F10 |
| Dodecafluoropentane | 678-26-2 | C5F12 |
| Tetradecafluorohexane | 355-42-0 | C6F14 |
| 1H-Perfluoropentane | 375-61-1 | C5HF11 |
| Hexadecafluoroheptane | 335-57-9 | C7F16 |
| Heptafluoropropyl-1,2,2,2-tetrafluoroethyl ether (E1) | 3330-15-2 | C5HF11O |
| 1H-Perfluorohexane | 355-37-3 | C6HF13 |
| 1H-Perfluoroheptane | 375-83-7 | C7HF15 |
| 2H-Perfluoro-5-methyl-3,6-dioxanonane (E2) | 3330-14-1 | C8HF17O2 |
| 1H-Perfluorooctane | 335-65-9 | C8HF17 |
| Octadecafluorooctane | 307-34-6 | C8F18 |
| 1H-Nonafluorobutane | 375-17-7 | C4HF9 |
| 1H-Heptafluoropropane | 2252-84-8 | C3HF7 |
| 1,1,1,2-Tetrafluoroethane (HFC-134a) | 811-97-2 | C2H2F4 |
| Chlorodifluoromethane (HCFC-22) | 75-45-6 | CHClF2 |
| Chlorotrifluoromethane (CFC-13) | 75-72-9 | CF3Cl |
| Octafluorocyclobutane (FC-C318) | 115-25-3 | C4F8 |
| Octafluorocyclopentene (FC-C1418) | 559-40-0 | C5F8 |
| Trichloromonofluoromethane (CFC-11) | 75-69-4 | CCl3F |

